Biograil

Biograil is a pre-clinical stage pharmaceutical company leveraging its proprietary BIONDD technology to unlock the potential of transforming the tremendous market of injectable pharmaceutical products into convenient oral capsules.

Proprietary Technology

Highly effective oral delivery of biologics that overcomes barriers of degradation and absorption

Verified Manufacturing Technology

Team behind Worlds first injection molded pharmaceutical product approved by the FDA

Strong Strategic Partnerships

Backed by Large International Pharmaceutical Company, leading experts in Bioresorbable Polymers, Drug Device & Pharmaceutical Development

the Solution

The majority of biologic pharmaceutical products are injected, as preferred dosing by the oral route is not feasible due to degradation and poor absorption from the gut.

The BIONDD technology provides a viable solution to safe and highly effective dosing of biologics in a standard oral capsule.


the Technology

The BIONDD technology provides a platform to deliver biologics by the oral route in a standard capsule, by specifically directing the biologic drug molecule inside the intestinal wall for safe and effective release to the body.

With release of the biologic drug molecule inside the intestinal wall the usual barriers (degradation and poor absorption from the gut) are circumvented. This results in highly effective oral delivery of the drug equivalent to an injection.

1
BIONDD in a standard capsule

2
…is swallowed and passed to the intestine.

3
Muscle contraction (peristalsis) pushes a tiny spike with drug safely into the gut wall.

4
The spike dissolves inside the gut wall

5
…and the drug distributes effectively throughout the body


INNOVATIVE. SAFE. EFFICACIOUS.

  • Novelty of the BIONDD technology is emphasized by published patent application with more in progress. Reports confirm strong patent position.
  • The design of BIONDD secures a safe and painless transient positioning of the spike inside the gut wall.
  • Preliminary data confirm highly effective delivery of drug from the gut wall, at least equivalent to an injection.


SIMPLE. SCALABLE. KNOW-HOW.

  • The design and function of BIONDD is strikingly elegant, and is specifically developed with manufacturing simplicity and scalability in mind.
  • Developed on the foundation of reverse engineering to secure low-cost high-volume commercial manufacturing by injection molding.
  • The Biograil team is behind the World’s first FDA approved drug product manufactured by injection molding.


APPLICABLE.

  • BIONDD has potential to transform markets of injectable pharmaceutical products across a wide range of therapeutic drug classes by providing safe, effective, and convenient oral treatment of a range of diseases.
  • Patients tend to avoid injections and overwhelmingly prefer oral capsules, which results in better treatment. Contrary to injections, oral capsules are pleaseant to dose, easy to do correctly, and not stigmatizing.


News

2020-04-30

Press Release: Biograil announces – Sanner Ventures has joined Investor Syndicate

2020-04-08

CEO Karsten Lindhardt shares vision for Biograil, by MEGATREND INVEST

2020-01-15

Press Release: Biograil Secures Seed Funding for Oral Delivery Device with Potential to Transform Market for Injectables

Biograil ApS
Baldersbuen 2
2640 Hedehusene
Denmark

E: info@biograil.com
T: +45 21 66 39 41