The BIONDD™ technology provides a platform to deliver biologics by the oral route in a standard capsule, by specifically directing the biologic drug molecule inside the stomach wall for safe and effective release to the body.
With release of the biologic drug molecule inside the stomach wall the usual barriers for dosing by the oral route (degradation and poor absorption from the gut) are circumvented. This results in highly effective oral delivery of the drug equivalent to an injection.
Proprietary Technology
Highly effective oral delivery of biologics that overcomes barriers of degradation and absorption
Verified Manufacturing Technology
Team behind Worlds first injection molded pharmaceutical product approved by the FDA
Strong Strategic Partnerships
Backed by Big Pharma, Leading Experts in Bioresorbable Polymers, Drug Device & Pharmaceutical Development
The Technology
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BIONDD™ in a standard size 00 capsule
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…is swallowed and is activated after 3 minutes in the stomach
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The device rotates two halves in opposite direction with small spikes extending
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The spikes embrace tissue from both sides and secure a safe and painless transient positioning of the spike inside the stomach wall
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The biodegradable spikes detach, releasing drug from the spikes for effective distribution into the blood stream
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…and throughout the body
INNOVATIVE. EFFICACIOUS. SAFE.
- Strong patent position with published applications and more in progress
- Data confirms highly effective delivery of drug from the gut wall, often superior to a skin injection
- BIONDD™ secures a safe and painless transient positioning of the spike inside the stomach wall
SIMPLE. SCALABLE. KNOW-HOW.
- BIONDD™ is strikingly elegant, specifically developed with manufacturing simplicity and scalability in mind
- Developed on the foundation of reverse engineering for low-cost high-volume commercial manufacturing by injection molding
- The Biograil team is behind the World’s first FDA approved drug product manufactured by injection molding
APPLICABLE.
- BIONDD™ has potential to transform markets of injectable pharmaceutical products across a wide range of therapeutic drug classes by providing effective, safe and convenient oral treatment to a range of diseases.
- Patients tend to avoid injections and overwhelmingly prefer oral capsules, which results in better treatment. Contrary to injections, oral capsules are pleaseant to dose, easy to do correctly, and not stigmatizing.